Communication Destinations
Use
You must define the following communication destinations:
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System address, port number and client number. This information is used by the mobile client to synchronize with the Data Orchestration Engine (DOE)
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RFC destinations for the connecting the DOE to the back-end systems
Try to define the RFC destinations so that there is an RFC Trusted System network
More information: Network Safety and Communications section, in SAP NetWeaver security guide.